Lower Division Courses numbered 1–99 are designed primarily for freshmen and sophomores but are open to all students for lower division credit. (Graduate students requesting to enroll in lower-division undergraduate courses will not receive unit credit nor will the course fulfill degree requirements.)
Upper Division Courses courses numbered 100–199 are open to all students who have met the necessary prerequisites as indicated in the catalog course description. Preparation should generally include completion of one lower division course in the given subject or completion of two years of college work.
GRADUATE COURSES
Courses numbered 200–299 are open to graduate students. (Undergraduate students must obtain the signature of the instructor, School Dean, and the Dean of Graduate Studies. Graduate level units will count towards the required 120 units for graduation; however students are urged to meet with their academic advisor in order to determine if graduate course units may be used to fulfill a graduation requirement.)
CROSS-LISTED/CONJOINED COURSES
Cross-listed Courses are the same course offered under different course subjects at the same level (either undergraduate or graduate) that share the same meeting time, requirements, units, etc. Conjoined Courses are the same course but one is undergraduate and one is graduate.
COREQUISITE COURSE
A corequisite course is a course that must be taken at the same time as another course.
PREREQUISITES
Prerequisites for courses should be followed carefully; the responsibility for meeting these requirements rests on the student. If you can demonstrate that your preparation is equivalent to that specified by the prerequisites, the instructor may waive these requirements for you. The instructor also may request that a student who has not completed the prerequisites be dropped from the course. If the prerequisite for a course is not satisfied, students must obtain the approval of the instructor (or school designee) of the course they wish to take.
For all undergraduate courses a “C-” or better grade is required for a course to be used as a prerequisite for another course. If a course was taken for a “P/NP” grade then a “P” grade is required.
For all graduate courses a “B” or better grade is required for a course to be used as a prerequisite for another course. If a course was taken for a “S/U” grade then a “S” grade is required.
WORLD LANGUAGES
No credit is allowed for completing a less advanced course after successful completion (C-or better) of a more advanced course in the world languages. This applies only to lower division world language courses, not upper division courses.
GRADING OPTIONS
Unless otherwise stated in the course description, each course is letter graded with a P/NP or S/U option (unless required for your major or graduate program). The policy regarding Grading Options, can be found in an alternate section of the catalog.
Special Topics in Materials covers background principles of cutting-edge research directions in the field of material science. Includes 3 hours of lecture and discussion per week and significant out-of-class reading and study. The course format also emphasizes student-led presentation, analysis and discussion of reading assignments from the current and recent scientific literature.
Course Details Repeats Allowed for Credit: 0
Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: MATH 021 and PHYS 008 and BIO 002 Instructor Permission Required: No
Application of kinetic principles to the study of mass transport processes transformations, and reactions. Thermal activation and rates of processes; nucleation and growth; phase transformations; control of micro- and nano-structure. Case studies relevant to the processing of metals, polymers, ceramics, and nanomaterials. Undergraduate preparation in introductory calculus, physics, chemistry, and thermodynamics highly recommended.
Course Details Repeats Allowed for Credit: 0
Conjoined with: MSE 111 Discussion included Normal Letter Grade only
Requisites and Restrictions Instructor Permission Required: No
The field of synthetic biology is quickly emerging as potentially one of the most important and profound ways by which we can understand and manipulate our physical world for desired purposes. While synthetic biology builds upon existing areas, such as genetic engineering, systems biology, and non-biological fields such as computer science, it is becoming evident that synthetic biology represents its own new engineering discipline. At the heart of synthetic biology is the aim to make the engineering of new biological functions predictable, safe, and quick and to aid in creating biological applications of benefit to society. Relevant topics in cellular and molecular biology and biophysics, dynamical and engineering systems, and design and operation of natural and synthetic circuits are covered in a concise manner that than allows the students to begin to design new biology-based systems.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade only
Requisites and Restrictions Open only to following major/minor(s):
BEST 217: Lab on a Chip: Developing 3rd World Diagnostics for Global Health
Units: 3
This first-ever four campus course between UC San Francisco, UC Berkeley, UC Santa Cruz, and UC Merced aims to 1) raise awareness and knowledge about global health issues 2) teach students critical engineering skills such as nano/micro-fabrication 3) enable students to design, build, and test their own diagnostics and 4) develop entrepreneurial skills. Students learn about tuberculosis from leading experts at UCSF and then address the dearth of sensitive diagnostics by designing and testing their own nano/micro-systems. Taught at UC Merced with tele-conferencing to the other campuses and two field trips.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: QSB 217 Laboratory included Normal Letter Grade only
Requisites and Restrictions Instructor Permission Required: No
BEST 218: Advanced Bio-thermodynamics, Bio-kinetics, and Bio-transport
Units: 4
Focuses on thermodynamic aspects, kinetics and transport within living and biochemical systems, designed for emerging engineering disciplines that deal with living systems. Aims to provide theoretical and conceptual principles underlying biomolecular and biological systems.
Course Details Repeats Allowed for Credit: 0
Normal Letter Grade only
Requisites and Restrictions Instructor Permission Required: No Knowledge of thermodynamics and either fluid mechanics or bio-transport phenomena strongly recommended.
BEST 226: Nanodevice Fabrication: Bridging Research and Education
Units: 4
Basic properties of nanomaterials and their applications as transducers (the lecture part). Nanomaterial synthesis using both solution and vapor-based approaches will be performed and a transducer will be fabricated and tested (the lab part). The interactive and experiential education will be blended with theoretical concepts.
Course Details Repeats Allowed for Credit: 0
Conjoined with: MSE 126 Laboratory included Normal Letter Grade only
Requisites and Restrictions Instructor Permission Required: No
BEST 230: Computation and Modeling for Interdisciplinary Biophysical Sciences, Biomaterials and Biotechnology
Units: 3
Covers cutting-edge applications of computation and modeling tools to problems in biophysical sciences, biomaterials and biotechnology. Team of students will undertake open research projects utilizing tools and languages such as R, Python and C/C++ to address questions ranging from epidemic spreading to protein design.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: BIOE 230, PHYS 230 Discussion included Normal Letter Grade only
Requisites and Restrictions Instructor Permission Required: No Completion of the NSF-CREST CCBM IB3 Summer Training Module in Computation and Modeling is strongly recommended.
BEST 232: Bio and Nano Fabrication for Interdisciplinary Biophysical Sciences, Biomaterials and Biotechnology
Units: 3
Covers cutting-edge applications of fabrication tools to problems in biophysical sciences, biomaterials and biotechnology. Teams of students will undertake open research projects utilizing tools such as lithography, electrospinning, cell culture and confocal microscopy to explore cellular and multicellular systems.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: PHYS 232, BIOE 232 Discussion included Normal Letter Grade only
Requisites and Restrictions Instructor Permission Required: No Completion of the NSF-CREST CCBM IB3 Summer Training Module in Nano Biofabrication is strongly recommended.
Focuses on the analysis and design of custom biomolecules, including proteins, nucleic acids, and macromolecular complexes. Students will learn the experimental and computational tools/approaches for engineering biomolecules and how to apply these new technologies to solving some of the most pressing problems in biotechnology, medicine and bioengineering.
Course Details Repeats Allowed for Credit: 0
Normal Letter Grade only
Requisites and Restrictions Instructor Permission Required: No
BEST 285: Seminar: Nanomaterials for Space Exploration
Units: 1
Designed for students in materials engineering, physics, and chemistry. Intended to expose students to various nanomaterial-based devices, foster students’ critical thinking in postulating feasible approaches, and develop students’ communication and presentation skills.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: CHEM 285, ME 285, PHYS 285 Normal Letter Grade only
Requisites and Restrictions Instructor Permission Required: No
Introduces the major concepts in biology including origin of life, evolution, DNA, genes and genomes. Principles and patterns of inheritance, biotechnology, biodiversity, earth systems, environments and disease relationships in addition to ecosystem structures, function, nutrient cycles, pollution, and genotypes to phenotypes.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade only
GE Requirements
Badge: Scientific Method
Badge: Quantitative and Numerical Analysis
Badge: Sustainability
Requisites and Restrictions Prerequisite Courses with Concurrent Option: BIO 001L Open only to following major/minor(s):
Introduces the molecules and molecular processes underlying life. Overview of structures and chemical properties of biological macromolecules.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade only
GE Requirements
Badge: Scientific Method
Requisites and Restrictions Prerequisite Courses: BIO 001 or equivalent exam Prerequisite Courses with Concurrent Option: BIO 002L Open only to following major/minor(s):
Fundamental biological concepts in the areas of genetics, evolution and ecology are explored in the context of current issues enabling students to understand the relevance of biology to their lives both as individuals and as voting citizens.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
GE Requirements
Approaches to Knowledge: Natural Science
Badge: Scientific Method
Requisites and Restrictions Cannot be taken for credit after successfully completing: BIO 001, BIO 002 Instructor Permission Required: No Not recommended for BIO majors
Analytical and computational methods for statistical analysis of data. Descriptive statistics, graphical representations of data, correlation, regression, experiment design, introductory probability, random variables, sampling distributions, inference, and significance.
Course Details Repeats Allowed for Credit: 1
Discussion included Normal Letter Grade only
GE Requirements
Badge: Quantitative and Numerical Analysis
Requisites and Restrictions Prerequisite Courses: MATH 005 or MATH 011 or MATH 021 or equivalent exam Cannot be taken for credit after successfully completing: MATH 032 Instructor Permission Required: No
An introduction to biological, chemical, and physical oceanography, marine geomorphology, and their synthesis in the study of marine life; also including relationships with atmospheric, freshwater, and terrestrial systems. Areas of emphasis include ecosystems (from the deep sea to saltwater ponds), the integrated coastal zone, resource management, and global change.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 034 Discussion included Normal Letter Grade with Pass/No Pass option
GE Requirements
Badge: Scientific Method
Badge: Literary and Textual Analysis
Badge: Quantitative and Numerical Analysis
Badge: Global Awareness
Badge: Sustainability
Badge: Ethics
Requisites and Restrictions Instructor Permission Required: No
Introduction to the study of biodiversity and conservation. Patterns, origin, and importance of biodiversity are discussed. An introduction to the major biological groups and the conservation efforts used to preserve contemporary biodiversity.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 043 Discussion included Normal Letter Grade with Pass/No Pass option
GE Requirements
Approaches to Knowledge: Natural Science
Badge: Ethics
Badge: Global Awareness
Badge: Quantitative and Numerical Analysis
Badge: Sustainability
Badge: Scientific Method
Requisites and Restrictions Instructor Permission Required: No
Dinosaurs are used to explore the development of science and fundamental concepts of geology, evolution, and biodiversity. Students are also introduced to basic anatomy and the underlying unity of animal form. Current controversies such as mass extinctions are explored, and students weigh evidence in coming to their own interpretations.
Course Details Repeats Allowed for Credit: 0
Discussion and Laboratory included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Instructor Permission Required: No
Astrobiology refers to the study of the origin and evolution of life in the cosmos: What is life, how did it form, and where is it? It is an integrative, multidisciplinary field that includes areas of astronomy, biology, (bio)chemistry, geology, and physics.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 047 Discussion included Normal Letter Grade only
GE Requirements
Approaches to Knowledge: Natural Science
Badge: Ethics
Requisites and Restrictions Instructor Permission Required: No
Male and female reproductive systems, hormonal control of egg-sperm interactions, fertilization, venereal disease, embryonic development, fetal physiology.
Course Details Repeats Allowed for Credit: 0
Discussion and Laboratory included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Instructor Permission Required: No
Introduction to the biology of cancer and aging, including discussions of the biological and molecular basis of aging and cancer, novel and conventional cancer treatments, cancer prevention, and prospects for new approaches to increase longevity and health.
Course Details Repeats Allowed for Credit: 0
Discussion and Laboratory included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Instructor Permission Required: No
Introduction to nutrition science that integrates basic concepts of nutrients, human physiology, microbiology, biochemistry, and the psychology of wellness.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
GE Requirements
Approaches to Knowledge: Natural Science
Requisites and Restrictions Instructor Permission Required: No
Provides an introduction to the history of life, emphasizing the radiation of dinosaur species throughout the Mesozoic Era, and ecological roles filled by different dinosaur groups. Connections will be made between the ecological, and environmental events shaping the Mesozoic and those experienced throughout the Anthropocene.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 065 Discussion included Normal Letter Grade only
Requisites and Restrictions Instructor Permission Required: No
BIO 102: Advanced Biochemistry and Molecular Biology
Units: 4
Mechanisms of amino acid, nucleic acid, and lipid metabolism plus advanced mechanisms of gene expression, signal transduction, and regulation of gene expression.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: CHEM 122 Discussion and Laboratory included Normal Letter Grade only
GE Requirements
Badge: Scientific Method
Requisites and Restrictions Prerequisite Courses: BIO 101 Instructor Permission Required: No
Aims to give students an understanding of relevant physical principles for biological systems, introduce them to experimental and theoretical techniques of biophysics and to communicate the excitement of cutting-edge biophysics research. Topics include diffusion, fluids, entropic forces, motor proteins, enzymes, nerve impulses, networks and evolution.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: PHYS 104 Conjoined with: PHYS 204 Discussion included Normal Letter Grade only
GE Requirements
Approaches to Knowledge: Natural Science
Badge: Quantitative and Numerical Analysis
Requisites and Restrictions Prerequisite Courses: (PHYS 018 or PHYS 008 or PHYS 008H or equivalent exam) and (PHYS 019 or PHYS 009 or PHYS 009H) Instructor Permission Required: No
Laboratory experiments demonstrating and reinforcing topics covered in BIO 104.
Course Details Repeats Allowed for Credit: 0
Laboratory included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: (BIO 101 or BIO 002) and (ENGR 130 or CHEM 010 or CHEM 010H or equivalent exam) Prerequisite Courses with Concurrent Option: BIO 104 Instructor Permission Required: No
Laboratory experiments demonstrating and reinforcing topics covered in BIO 105.
Course Details Repeats Allowed for Credit: 0
Laboratory included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: BIO 002 and (CHEM 010 or CHEM 010H or equivalent exam) Corequisite Courses: BIO 105 Instructor Permission Required: No
Introduction to the structure and function of bacterial, plant and animal cells, with an emphasis on universal cellular systems, including regulation of sub-cellular organization, control of cellular processes by internal and external signaling, energy capture, storage and usage, and cell cycle.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade only
GE Requirements
Badge: Scientific Method
Badge: Media and Visual Analysis
Badge: Quantitative and Numerical Analysis
Requisites and Restrictions Prerequisite Courses: BIO 002 and (CHEM 010 or CHEM 010H) Instructor Permission Required: No
Introduction to principles of cell structure and the organization of cells into tissues, organs, and organ systems. Both the cellular and extracellular components of the primary tissues and their compilation into the major organic systems are covered. Emphasis on understanding the link between cellular architectures and organ function.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: BIO 110 Instructor Permission Required: No
Teaches intermediate-level concepts in sustainability and Anthropocene studies in the context of societal issues facing this and future generations. The goal is to help prepare students to effectively interpret, generate, and use data and multiple modes of communication in future venues as a researcher or a citizen.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 113 Discussion included Normal Letter Grade only
GE Requirements
Upper Division: Crossroads
Approaches to Knowledge: Natural Science
Badge: Scientific Method
Badge: Global Awareness
Badge: Sustainability
Requisites and Restrictions Open only to the following class level(s):
Molecular basis for diversity in bacteria and archae. Students explore the significance of molecular diversity in microbial biology and gain an understanding of the genetic, physiologic, and structure-function relationships that underlie the remarkable ability of these organisms to adapt to the environment.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: BIO 110 Instructor Permission Required: No
Involving laboratory experiments the course demonstrates and reinforces topics covered in BIO120. Topics explored include microbiological techniques, microscopy, microbial growth, structures and motility, microbial metabolism and biochemistry, molecular biology of microbes, microbial development and microbial relationships.
Course Details Repeats Allowed for Credit: 0
Laboratory included Normal Letter Grade only
GE Requirements
Badge: Practical and Applied Knowledge
Upper Division: Writing in the Discipline
Requisites and Restrictions Prerequisite Courses with Concurrent Option: BIO 120 Open only to following major/minor(s):
BIO 121: Introduction to Ecological and Environmental Microbiology
Units: 4
Fundamentals of microbiology in ecological and environmental systems, including the distribution of microbial diversity throughout terrestrial, ‘extreme,’ and marine environments; microbial control of global biogeochemical cycles; and environmental services provided by microorganisms. Both classical and contemporary biochemical, molecular, and genomic approaches to microbial physiology, metabolism, and ecology will be discussed.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 120 Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: (CHEM 010 or CHEM 010H or equivalent exam) and (ESS 001 or BIO 001 or ENVE 020 or equivalent exam) Instructor Permission Required: No
Covers the biology of medically important microorganisms, including bacterial and fungal pathogens. Focuses on the mechanisms and epidemiology of infectious diseases, with an emphasis on the strategies used by microorganisms to infect their hosts.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 120 or BIO 151 Instructor Permission Required: No
Introduction to protozoan and helminth parasitism in animals and humans and resultant diseases. Emphasis will be on epidemiology, biology, and immunology of parasitic infections.
Course Details Repeats Allowed for Credit: 0
Conjoined with: QSB 223 Discussion included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 120 or BIO 151 Instructor Permission Required: No
Evolution of microbes. Concepts covered include horizontal exchange, genome evolution, dispersal of microbes, population size, cryptic genes, mutagenesis and mutagenic pathways, phylogenetics, experimental evolution, metabolic evolution and antimicrobial resistance evolution.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade only
GE Requirements
Badge: Scientific Method
Badge: Literary and Textual Analysis
Badge: Quantitative and Numerical Analysis
Badge: Diversity and Identity
Badge: Leadership, Community, and Engaging the World
Requisites and Restrictions Prerequisite Courses with Concurrent Option: BIO 110 Instructor Permission Required: No
Introduction to biology of bacterial and animal viruses, focusing on structure, infective cycle, interactions with host, transmission and methods of detection and control. Discusses scientific literature and current topics in virology.
Course Details Repeats Allowed for Credit: 0
Conjoined with: QSB 227 Discussion included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses with Concurrent Option: BIO 110 Instructor Permission Required: No BIO 140 strongly recommended
Introduction to discovery-based research through a two-semester experience. In the first semester, students isolate bacteriophages (bacterial viruses), purify and characterize them by restriction digestion and electron microscopy, and prepare viral genomic DNA for sequencing in the first semester. Students are expected to enroll in the second semester to complete the two-semester discovery-based research experience.
Course Details Repeats Allowed for Credit: 0
Laboratory included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 002 and BIO 002L Open only to following major/minor(s):
Applied Mathematical Sciences (Undergraduate) - MATH
Introduction to discovery-based research through a two-semester experience. In the second semester, students receive genomic sequences from previously isolated and characterized bacteriophages. Students then employ bioinformatics methods to annotate the bacteriophage’s genome sequence. After quality control checks, the students’ annotated sequence is submitted to the GenBank database. Students present their isolated, characterized, and annotated bacteriophage in a poster presentation, which completes the two-semester discovery-based research experience.
Course Details Repeats Allowed for Credit: 0
Laboratory included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 127LA Open only to following major/minor(s):
Applied Mathematical Sciences (Undergraduate) - MATH
Introduction to the relationships of fossil organisms to one another and to their physical environment, focusing on terrestrial paleoecology of the past 2.5 million years. This class will introduce past environments, discuss common proxies for studying paleoecology, and examine ecological principles as applied to the past.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 129 Conjoined with: ES 229 Normal Letter Grade only
GE Requirements
Upper Division: Crossroads
Upper Division: Writing in the Discipline
Badge: Scientific Method
Badge: Literary and Textual Analysis
Badge: Sustainability
Badge: Practical and Applied Knowledge
Requisites and Restrictions Prerequisite Courses: (BIO 148 or ESS 148) and (one lower-division BIO or ESS course, or equivalent exam) Instructor Permission Required: No
Introduces students to the basics of plant biology. Topics covered include plant biochemistry and metabolism, anatomy, reproduction, evolution, and ecological interactions, as well as the interactions between plants and humans in the context of agriculture, medicine, and global change.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 130 Laboratory included Normal Letter Grade only
GE Requirements
Approaches to Knowledge: Natural Science
Badge: Literary and Textual Analysis
Badge: Scientific Method
Badge: Sustainability
Upper Division: Crossroads
Upper Division: Writing in the Discipline
Requisites and Restrictions Prerequisite Courses: (BIO 001 or BIO 148 or ESS 148 or equivalent exam) and (CHEM 002 or CHEM 002H or equivalent exam) Open only to the following class level(s):
An introduction to the plant diversity of California. It consists of lectures and labs focusing on plant identification in the foothills of the Central Sierra Nevada and covers concepts such as endemism, plant/soil interactions, and vegetation types.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 133 Conjoined with: ES 227 Laboratory included Normal Letter Grade with Pass/No Pass option
GE Requirements
Upper Division: Crossroads
Requisites and Restrictions Prerequisite Courses: BIO 001 or ESS 001 or BIO 148 or ESS 050 or equivalent exam Open only to the following class level(s):
Integrative studies of ocean and coastal ecosystems, including current issues. Also referencing relationships with atmospheric, freshwater, and terrestrial systems.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 135 Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 141 or BIO 148 Open only to the following class level(s):
Includes concepts of inheritance, structure and function of genes and genomes, recombination, genetic mapping, gene regulation, mutations, and recombinant DNA technology including labs and discussions.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 002 Prerequisite Courses with Concurrent Option: (MATH 012 or MATH 022) and (MATH 018 or BIO 018 or MATH 032 or ENVE 105 or PSY 010 or equivalent course accepted by the Biology major or equivalent exam) Instructor Permission Required: No
Explores the fundamentals of modern evolutionary biology, including natural selection, population genetics, molecular evolution, speciation, and phylogenetics.
Course Details Repeats Allowed for Credit: 0
Laboratory included Normal Letter Grade only
GE Requirements
Approaches to Knowledge: Natural Science
Badge: Practical and Applied Knowledge
Badge: Scientific Method
Upper Division: Writing in the Discipline
Requisites and Restrictions Prerequisite Courses: (BIO 001 or equivalent exam) and BIO 002 Instructor Permission Required: No
Introduction to the concepts behind genome biology and a detailed overview of the many tools used in comparative genomics. Specific topics include genome assembly, gene modeling and comparative genomics, transcriptomics, and proteomics of prokaryotic and eukaryotic organisms. Students carry out real scientific projects in collaboration with course faculty and produce new genomic data of publishable quality. Includes mandatory weekly three hour lab.
Course Details Repeats Allowed for Credit: 0
Discussion and Laboratory included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 110 Instructor Permission Required: No
Introduction to the biological diversity in the three domains of the Tree of Life (Archaebacteria, Eubacteria, and Eukaryotes): overview of species diversity as well as diversity in the deep characteristics (e.g., reproduction, metabolism, structure) of plants, animals, fungi, and microbes. Illustrated by complementary field trips and labs (part of BIO 143F).
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 001 or equivalent exam Instructor Permission Required: No
Field trips and labs reinforcing topics covered in BIO 143. Five field trips illustrate the biodiversity of different regions of California (seashore, Central Valley, foothills, and Sierra Nevada). Wet labs serve to examine the organisms collected during field trips, and participate in a long-term DNA Barcoding project of the field sites visited.
Course Details Repeats Allowed for Credit: 0
Laboratory included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 001 or equivalent exam Corequisite Courses: BIO 143 Instructor Permission Required: No
Theory behind phylogenetic reconstruction and an introduction to the diverse methods for phylogenetic inference. How to deal with morphological and molecular characters is discussed as well as the comparative method.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: BIO 140 and (MATH 032 or MATH 018 or BIO 018 or equivalent exam) Instructor Permission Required: No
BIO 145: Introduction to Population and Community Ecology
Units: 4
Comprehensive introduction to the ecology of populations, communities and ecosystems. Examines the dynamics of single-species populations, and then moves to species interactions including competition, predation, parasitism, and mutualism. Structure and dynamics of entire communities and food webs also are examined. Discusses conservation biology applications throughout.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: (BIO 001 or equivalent exam) and (MATH 021 or equivalent exam) Instructor Permission Required: No
An introduction to the major geological factors that have affected the evolution and the diversity of organisms. We also present how the fossil record can help us understand evolution of Life through time, with an emphasis on macro-evolutionary events (e.g., mass extinctions, transitions between habitats, radiations).
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: BIO 140 Instructor Permission Required: No
Supports field and lab activities for BIO 148 and ESS 148 and will reinforce class activities. Some lessons will occur off campus and students will need to arrange transportation.
Course Details Repeats Allowed for Credit: 0
Laboratory included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses with Concurrent Option: BIO 148 or ESS 148 Instructor Permission Required: No
Detailed examination of the evolutionary, ecological, management, and policy issues related to the conservation of ecosystems, species, and genetic diversity. Theory and practical aspects of biological conservation are also presented, with special reference to case studies from California.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 149 Discussion included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: (BIO 001 or equivalent exam) and (MATH 018 or BIO 018 or MATH 032 or equivalent exam) Instructor Permission Required: No BIO 148 recommended
Principles of developmental biology as revealed through analysis of invertebrate and vertebrate systems. Animal models are used to examine the molecular and cellular mechanisms that influence cell fate. Cell signaling is studied in the context of embryonic pattern formation and the development of body plans and organ systems.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: BIO 110 Instructor Permission Required: No
Emphasis on development and function of hematopoietic and immune systems and their roles in responding to environmental change, maintenance of health, and disease pathogenesis.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: BIO 110 Instructor Permission Required: No
Topics include viral and hormonal carcinogenesis, molecular aberrations in cancer, tumor development, epigenetics and cancer, tumor immunology, oncogenes.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: BIO 101 or BIO 110 Instructor Permission Required: No
Comparison and contrast of the development and developmental cues of a variety of animals and emphasizes how conserved developmental pathways have been manipulated through evolutionary processes to produce different physical features. The effects of regulatory region mutations, gene duplication, and genetic co-opting are investigated.
Course Details Repeats Allowed for Credit: 0
Conjoined with: QSB 253 Discussion included Normal Letter Grade only
GE Requirements
Upper Division: Crossroads
Approaches to Knowledge: Natural Science
Badge: Scientific Method
Badge: Literary and Textual Analysis
Badge: Quantitative and Numerical Analysis
Requisites and Restrictions Prerequisite Courses: BIO 110 Instructor Permission Required: No
An in-depth exploration of the development of the immune system. Topics include the biology of primary lymphoid organs (particularly the thymus and bone marrow) and early development of lymphoid and myeloid cells. Emphasis is on the temporal, microenvironmental, genetic and molecular control of immune cell development.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 151 or BIO 150 Open only to the following class level(s):
Focuses on symbiotic interactions between eukaryotes and microbes, and the molecular and genetic techniques that enable their study. Course materials focus on the fundamental concepts of symbioses; their evolution, ecology, and role in plant- animal- and human health. Includes a genomics bioinformatics lab component and individual research projects.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 155 Laboratory included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 002 and BIO 140 Instructor Permission Required: No
Introduction to theoretical ecology, involving a tour through population dynamics, stochastic processes, and ecological networks. Students will become familiar and comfortable with basic theoretical models in ecology and understand how these models are used to gain information about biological systems.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 156 Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: (BIO 001 or equivalent exam) and (MATH 021 or equivalent exam) Instructor Permission Required: No
Ecosystem ecology is the study of interactions between organisms and their physical environment within an Earth-system context. Focuses on energy, water, and nutrient flows through the living (plants, animals, microorganisms) and nonliving (soils, atmosphere) components of both natural and human-modified terrestrial ecosystems.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 124 Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: BIO 148 or ESS 148 Open only to the following class level(s):
Explores the global diversity of amphibians and reptiles, their evolution, unique phenotypes, the environments they occupy, their behavior and reproduction, physiology and conservation. This course has a focus on California herpetological diversity.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 141 Instructor Permission Required: No
Covers the function of the major organ systems by studying species-specific adaptations across the vertebrate subphylum, emphasizing physiological adaptations to environmental challenges. Locomotion, reproduction, cardiovascular, renal, and pulmonary function serve as the models for assessing the cellular basis for physiologic adaptation across the spectrum of vertebrates.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: BIO 002 or BIO 101 Instructor Permission Required: No
Understanding the mechanisms underlying function of major human organs. Emphasis includes neural transmission and action potential, cardiovascular, renal and gastrointestinal physiology, metabolism, and endocrinology. Laboratory experiments demonstrating and reinforcing topics covered in lecture with an emphasis on scientific method.
Course Details Repeats Allowed for Credit: 0
Conjoined with: QSB 261 Laboratory included Normal Letter Grade only
GE Requirements
Upper Division: Writing in the Discipline
Approaches to Knowledge: Natural Science
Badge: Scientific Method
Badge: Quantitative and Numerical Analysis
Badge: Practical and Applied Knowledge
Requisites and Restrictions Prerequisite Courses: BIO 101 or CHEM 111 Prerequisite Courses with Concurrent Option: PHYS 009 or PHYS 009H or PHYS 019 Instructor Permission Required: No
An introduction to the materials upon which evolution acts. We study the structure of animals, the materials from which living organisms are made and the limitations that those materials impose upon evolution.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: BIO 160 Instructor Permission Required: No
Explores a lab-based approach to teach basic principles of endocrinology including: (1) the structure and function of endocrine glands primarily in mammals with reference to other vertebrates for comparison, (2) hormonal control of function such as renal, cardiovascular, neural, and substrate-level metabolism, and (3) mechanisms of hormone actions. In lab experiments are performed to re-enforce concepts and allow students to gain valuable lab skills and apply new techniques.
Course Details Repeats Allowed for Credit: 0
Laboratory included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses with Concurrent Option: BIO 101 or CHEM 111 Open only to the following class level(s):
Introduction to the basic concepts of human anatomy at the cell, tissue, and organ levels, through a system-based approach (e.g., skeletal, muscular, nervous, cardiovascular, respiratory, digestive, urinary, reproductive). Laboratories include dissection of mammal organs (cat, sheep, cow), observation of human models and histological slides of human tissues, and interactive computer based exercises.
Course Details Repeats Allowed for Credit: 0
Discussion and Laboratory included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 110 Open only to the following class level(s):
Explores cells and the surrounding intercellular components that together constitute particular patterns called tissues. Different tissues combine to form organs. Histology is the study of tissues and their patterns in multicellular organisms. Special techniques are required to study the tissues by microscopy. This course involves learning these routine and special methods to understand the structure and function of the tissue systems in normal and diseased states through the use of hands-on laboratory exercises.
Course Details Repeats Allowed for Credit: 0
Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 002 Open only to the following class level(s):
Junior
Senior
Instructor Permission Required: Yes Prior knowledge of the principles of cell structure and the organization of cells into tissues, organs, and organ systems is recommended but not required.
Examination of the general operations of the central and peripheral nervous system. Covers cellular neuroscience, including the molecular basis of excitability, synaptic transmission, and neuronal signal transduction, as well as the organization and operations of the major neural systems associated with sensation, locomotion, and higher brain function.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
GE Requirements
Upper Division: Crossroads
Approaches to Knowledge: Natural Science
Requisites and Restrictions Prerequisite Courses: BIO 110 Instructor Permission Required: No
BIO 171: Neurobiology of Brain Dysfunction and Disorders
Units: 4
Teaches in-depth cellular- and molecular-based mechanisms of brain dysfunctions by drug abuse, altered neuronal activities, and neurodegenerative diseases. Fundamental neurobiology of the central nervous system, pharmacology/toxicology, and biochemistry and anatomy of the brain will also be covered.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: BIO 110 and BIO 170 Instructor Permission Required: No
BIO 172: Sustainability of Agricultural Ecosystems
Units: 4
Application of ecological theory to understand sustainable management of agricultural ecosystems at local to global scales. Topics include nutrient cycling, biodiversity, landscape connectivity, soil fertility, organic matter management, and climate resilience.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 172 Discussion included Normal Letter Grade only
GE Requirements
Upper Division: Crossroads
Badge: Global Awareness
Badge: Sustainability
Badge: Practical and Applied Knowledge
Requisites and Restrictions Prerequisite Courses: ESS 148 or BIO 148
Instructor Permission Required: No
BIO 174: Stable Isotopes in Ecology and Environmental Science
Units: 4
Focuses on the fundamentals of stable isotope ecology, biochemistry, and geochemistry using both lecture and lab. Isotope systematics for carbon, nitrogen, hydrogen, oxygen, sulfur, strontium, and neodymium and how they operate in plants, animals, soils, and microbes during modern and geological timescales will form the framework for the class. Corresponding lab section will teach sample preparation, hypothesis building, and research skills using stable isotopes.
Course Details Repeats Allowed for Credit: 0
Crosslisted with: ESS 174 Laboratory included Normal Letter Grade only
GE Requirements
Approaches to Knowledge: Natural Science
Upper Division: Crossroads
Upper Division: Writing in the Discipline
Requisites and Restrictions Open only to the following class level(s):
Advances in statistical techniques to investigate experimental data generated in molecular, cellular, and evolutionary biology, and health sciences research.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: (MATH 032 or BIO 018 or PSY 10 or equivalent exam) and (MATH 012 or MATH 022 or equivalent exam) Instructor Permission Required: No
Physiological systems underlying animal behavior, including the genetic basis for normal and abnormal behaviors. Topics include: history of behavioral genetics; nature vs. nurture; genetic model systems including worms, flies, and mice; molecular mechanisms underlying behavioral phenotypes; gene regulation in behavioral change; circuits; genetics of human behavior and psychiatric disorders.
Course Details Repeats Allowed for Credit: 1
Discussion included Normal Letter Grade only
GE Requirements
Approaches to Knowledge: Natural Science
Badge: Scientific Method
Upper Division: Crossroads
Requisites and Restrictions Prerequisite Courses: BIO 110 Prerequisite Courses with Concurrent Option: BIO 161 or BIO 170 or PSY 181 or COGS 144 Instructor Permission Required: No
Statistical analysis and mathematical modeling skills for life scientists. The first half of this course is about building statistical models of complex data sets and the second half is about using population models to describe demographic change, ecosystems and epidemics. Extensive computer laboratories using the “R” statistical language.
Course Details Repeats Allowed for Credit: 0
Discussion included Normal Letter Grade only
Requisites and Restrictions Prerequisite Courses: (BIO 002 or CHEM 111 or BIO 101) and (MATH 012 or MATH 022 or equivalent exam) and (MATH 018 or PSY 010 or MATH 032 or BIO 018 or equivalent exam) Instructor Permission Required: No Since this class is being converted to an online format, there is no longer the limitation of seats in a computer room for the lab/discussion sessions. However, during at least the first semester (S19) that this online course is offered, the 2 1-hour midterm and 3-hour final exams will be conducted in-person. Therefore, a suitable room or rooms will need to be available for these exams.
Uses lectures and laboratory exercises to teach the principles and practice of molecular modeling with a focus on simulations of biological macromolecules. Topics covered include classical molecular dynamics, molecular mechanics, docking, and visualization. The computational laboratories will involve simulations of systems including water, micelles, DNA, and proteins.
Course Details Repeats Allowed for Credit: 0
Conjoined with: QSB 281 Discussion and Laboratory included Normal Letter Grade with Pass/No Pass option
Requisites and Restrictions Prerequisite Courses: (BIO 001 or equivalent exam) and (CHEM 008 or CHEM 008H) and (MATH 011 or MATH 021 or equivalent exam) and (PHYS 008 or PHYS 008H or PHYS 018 or equivalent exam) and (MATH 015 or CSE 019 or CSE 020 or BIO 180 or equivalent exam) Instructor Permission Required: No
Detailed introduction to bioinformatics, including reproducibility in scientific computing, elements of data science and machine learning models, nonparametric and Bayesian approaches to statistical inference, analysis of frequencies and compositions, models of molecular evolution, BLAST theory, alignment and motif-finding algorithms, distance-based methods, linear modeling and error control for high-throughput omics experiments. This is an R/RStudio- and UNIX-command-line-based course that also teaches some coding skills in Python and Perl. Previous programming experience not assumed or required.
Course Details Repeats Allowed for Credit: 0
Discussion and Laboratory included Normal Letter Grade only
GE Requirements
Badge: Ethics
Badge: Quantitative and Numerical Analysis
Badge: Scientific Method
Requisites and Restrictions Prerequisite Courses: BIO 018 or MATH 018 or MATH 032 or PSY 010 or ECON 010 or equivalent exam Prerequisite Courses with Concurrent Option: BIO 140 Instructor Permission Required: No