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May 13, 2024
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QSB 297: Systems Biology: From Molecules to Metabolic Networks
[3 units]
Provides a rigorous introduction to the theories, tools, and applications of systems biology. The course is organized around the biological flow of information known as the central dogma of biology. In essence we translate DNA into RNA and extend this information into metabolic and cellular networks. The course introduces experimental and high throughput approaches for generating large datasets, theory, algorithms, and computational approaches for their analysis. Data for analysis will come from ongoing systems biology projects taking place in the Instructor’s lab (genomics, transcriptomics, proteomics, metabolomics, fluxomics) as well as those of collaborators at UC Merced and other nearby institutions (metagenomics, phosphoproteomics, chenomics). The course may take advantage of presentations by guest lecturers with expertise in one of the many aspects of systems biology, or one of the sciences upon which it crucially depends.
Prerequisite: QSB 297L . Systems Biology lab is a co-requisite for enrolling in QSB 297, though may be opted out of by instructor’s permission if students have taken coursework covering the material of QSB 297L. Normal Letter Grade only.
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