Jun 16, 2024  
2016-2017 Catalog 
    
2016-2017 Catalog [ARCHIVED CATALOG]

Course Descriptions


UNDERGRADUATE COURSES

Lower Division Courses numbered 1–99 are designed primarily for freshmen and sophomores but are open to all students for lower division credit. (Graduate students requesting to enroll in lower-division undergraduate courses will not receive unit credit nor will the course fulfill degree requirements.) Upper Division Courses courses numbered 100–199 are open to all students who have met the necessary prerequisites as indicated in the catalog course description. Preparation should generally include completion of one lower division course in the given subject or completion of two years of college work.

GRADUATE COURSES

Courses numbered 200–299 are open to graduate students. (Undergraduate students must obtain the signature of the instructor, School Dean, and the Dean of Graduate Studies. Graduate level units will count towards the required 120 units for graduation; however students are urged to meet with their academic advisor in order to determine if graduate course units may be used to fulfill a graduation requirement.)

CROSS-LISTED/CONJOINED COURSES

Cross-listed Courses are the same course offered under different course subjects at the same level (either undergraduate or graduate) that share the same meeting time, requirements, units, etc. Conjoined Courses are the same course but one is undergraduate and one is graduate.

COREQUISITE COURSE

A corequisite course is a course that must be taken at the same time as another course.

PREREQUISITES

Prerequisites for courses should be followed carefully; the responsibility for meeting these requirements rests on the student. If you can demonstrate that your preparation is equivalent to that specified by the prerequisites, the instructor may waive these requirements for you. The instructor also may request that a student who has not completed the prerequisites be dropped from the course. If the prerequisite for a course is not satisfied, students must obtain the approval of the instructor (or school designee) of the course they wish to take.

For all undergraduate courses a “C-” or better grade is required for a course to be used as a prerequisite for another course. If a course was taken for a “P/NP” grade then a “P” grade is required.

For all graduate courses a “B” or better grade is required for a course to be used as a prerequisite for another course. If a course was taken for a “S/U” grade then a “S” grade is required.

FOREIGN LANGUAGES

No credit is allowed for completing a less advanced course after successful completion (C-or better) of a more advanced course in the foreign languages. This applies only to lower division foreign language courses, not upper division courses. 

GRADING OPTIONS

Unless otherwise stated in the course description, each course is letter graded with a P/NP or S/U option (unless required for your major or graduate program). The policy regarding Grading Options , can be found in an alternate section of the catalog.

More information about Course Substitutions  and Course Materials and Services Fees  can be found in alternate areas of the catalog.

 

Public Health

  
  • PH 005: Global and International Public Health


    [4 units]

    An overview of the dynamic factors that produce global health challenges, including demographic changes, conflict, human rights abuses, migration, travel, food production and distribution, water resources, and market forces and economic factors. We will also examine their responsibilities towards global health as global citizens.

    Normal Letter Grade only.


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  • PH 100: Introduction to Epidemiology


    [4 units]

    Concentration on the non-random distribution of disease in human populations and demonstration of how disparities in human culture and behavior are related differences in disease risk by characteristics person, place and time. Patterns of disease will be examined from the agent-host-environment paradigm.

    Prerequisite: (PH 001  or PH 005 ) and (PSY 010  or MATH 018  or equivalent exam). Normal Letter Grade only.


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  • PH 102: Health Promotion


    [4 units]

    Health promotion is the process of enabling people to increase control over, and to improve, their health. This course provides students with an overview of the principles of health promotion and various theories developed to change health behavior and promote the health of individuals and societies.

    Prerequisite: PH 001  or PH 005 . Normal Letter Grade only.


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  • PH 103: Health Communication


    [4 units]

    An introduction to the science and practice of health communication. The course will also describe the essentials for effective health communication and social marketing, reaching target audiences, developing and testing effective messages, and evaluating the impact of a communication campaign.

    Prerequisite: PH 100  or PH 102 . Normal Letter Grade only.


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  • PH 104: Health and the Media


    [4 units]

    Covers the media’s influence on health. Special attention will be paid to how health disparities are covered in the media, and the effects these portrayals might have on minority and majority populations. The course will also cover social media and health.

    Prerequisite: PH 001  or PH 100  or PH 102  or PH 103 . Normal Letter Grade only.


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  • PH 105: Introduction to US Health Care System


    [4 units]

    Overview of the US Health Care system. Topics include development and organization of US health system, challenges in California and US, how providers and funders work together, current problems, previous attempts to improve coverage and access to health care, and health care in other countries compared to the US.

    Prerequisite: PH 001  or PH 005 . Normal Letter Grade only.


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  • PH 108: Health Care in the San Joaquin Valley


    [4 units]

    An introduction to the health and provision of health care in the San Joaquin Valley, including diagnosis, treatment, management, and prevention efforts. Students will be prepared to engage with health professionals and community organizations in the region.

    Prerequisite: (PH 001  or PH 005 ) and PH 112  and (PSY 010  or MATH 018  or equivalent exam). Open only to major(s) and minor(s): Public Health. Normal Letter Grade only.


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  • PH 110: Environmental Health


    [4 units]

    An overview of the principles of Environmental Health with particular emphasis on the interaction between people and the environment, including recognizing, assessing and controlling the impacts of people in their environment while gauging the impacts of the environment on the public.

    Prerequisite: BIO 001  or BIO 003  or PH 001  or PH 105  or PH 100  or equivalent exam. Normal Letter Grade only.


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  • PH 111: Social Epidemiology


    [4 units]

    Social epidemiology is the branch of epidemiology that explores how social forces affect human health and well being. In particular it asks how social interactions, human activities, social conditions, social problems, and other social arrangements affect determinants of health and yield differential health outcomes.

    Prerequisite: PH 100 . Open only to standing(s): Sophomore, Junior, Senior. Normal Letter Grade only.


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  • PH 112: Research Methods: Health Services Research and Public Health


    [4 units]

    An introduction to research in the public health, health services research, and healthcare evaluation. Includes both qualitative and quantitative research methods, using examples of research across a range of areas in health.

    Prerequisite: PH 100  and (PSY 010  or MATH 018  or equivalent exam). Normal Letter Grade only.


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  • PH 113: Latino and Immigrant Health


    [4 units]

    Examines predictors of health for refugees and immigrant to the US, and their descendants, paying particular attention to Latinos. Examines the effects of acculturation on health, and shifts in health and health-related behavioral outcomes between refugees or immigrants and second and third (and beyond) generations.

    Prerequisite: PH 001  or PH 005 . Normal Letter Grade only. Cross-Listed with CCST 113 .


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  • PH 115: Research Methods for Public Health: GIS Mapping


    [4 units]

    Designed to provide students with an overview of the theory and application of Geographic Information Systems (GIS) with particular emphasis on Public Health.

    Prerequisite: PH 001  or PH 100  or PH 105 . Normal Letter Grade only.


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  • PH 125: Emerging Public Health Threats


    [4 units]

    A multidisciplinary study of the historical, sociological, medical, and biological issues underlying new public health threats and the scientific and policy-based approaches to responding to these new threats.

    Prerequisite: PH 001  or PH 100  or PH 105  or PSY 124  or BIO 001  or BIO 003  or BIO 110  or equivalent exam. Normal Letter Grade only.


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  • PH 135: Public Health Genetics


    [4 units]

    Explores the structure of genes and the human genome, types of genetic variation, their mechanistic and evolutionary origins, their roles in shaping health, and the societal implications of genetic variation.

    Prerequisite: PH 001  or PH 005  or PH 100  or BIO 001  or PSY 001  or equivalent exam. Normal Letter Grade only. Cross-Listed with BIO 135 .


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  • PH 137: Insects and Public Health


    [4 units]

    An introduction to the science of entomology and its importance to Public Health. The course will cover how to identify insects and case studies of insect vectored diseases. Other topics include insects and allergies, insecticides and alternatives, medically important insects, and insects and environmental health.

    Open only to standing(s): Sophomore, Junior, Senior. Normal Letter Grade only.


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  • PH 181: Public Health Research


    [4 units]

    An internship/service learning experience with either a public health researcher or a local health provider or community group. The project will focus on a relevant public health issue and will be agreed upon by the researcher or host organization, student and course coordinator.

    Prerequisite: PH 108 . Permission of instructor required. Normal Letter Grade only.


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  • PH 185: Introduction to Health and Biomedical Ethics


    [4 units]

    An overview of health and biomedical ethics. The class will discuss the key moral principles that drive ethical reasoning related to health care, with discussions focusing on ethical concerns encountered by practitioners and researchers in fields of clinical medicine and public health.

    Prerequisite: BIO 001  or BIO 003  or PH 001  or PH 005  or equivalent exam. Normal Letter Grade only.


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  • PH 190: Topics in Public Health


    [4 units]

    Provides intensive treatment of a special topic or problem in public health. Reviews public health theory and research on the issue as well as coverage of the methodological principles and tools used to guide research in the area.

    Prerequisite: PH 001  or PH 005 . Normal Letter Grade only. Course may be repeated 3 times for credit.


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  • PH 195: Upper Division Undergraduate Research


    [1-5 units]

    Group or individual research projects in the public health under the supervision of a Public Health faculty member.

    Permission of instructor required. Normal Letter Grade only. Course may be repeated for credit.


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Public Policy

  
  • PUBP 001: Introduction to Public Policy


    [4 units]

    Interdisciplinary introduction to public policy and policy issues facing the American voter. Emphasis is on how difficult it is to arrive at an informed decision–not on determining what that decision ought to be. Examines a diverse set of policy topics, including environment, health, education, and social policy, among others.

    Normal Letter Grade only. Discussion included.


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  • PUBP 092: Internship in Public Policy


    [1-4 units]

    Provides oversight and structure for a student’s internship in a field of public policy in community organizations, professional research projects, etc. connected to the study of public policy. Requires students to write an original research paper or relevant product that demonstrates how the internship advanced their knowledge of public policy.

    Permission of instructor required. Pass/Fail only. Course may be repeated 2 times for credit.


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  • PUBP 095: Lower Division Undergraduate Research


    [1-5 units]

    Supervised research.

    Permission of instructor required. Course may be repeated for credit.


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  • PUBP 098: Lower Division Directed Group Study


    [1-5 units]

    Permission of instructor required. Pass/Fail only. Course may be repeated for credit.


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  • PUBP 099: Lower Division Individual Study


    [1-5 units]

    Permission of instructor required. Pass/Fail only. Course may be repeated for credit.


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  • PUBP 100: Political Process and Institutions


    [4 units]

    Political and governmental context of policy, form agenda setting to evaluation. Course examines the context for setting constitutional, federal and local policy, as well as processes by which governmental institutions make decisions. We also examine interactions between institutions and approaches that further policy decision making.

    Prerequisite: PUBP 001  or POLI 001  or equivalent exam. Normal Letter Grade only.


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  • PUBP 110: Poverty and Social Policy


    [4 units]

    Overview of poverty and social policy in the United States in a historical context from the nineteen century until the present. Discusses current policy issues and policy debates surrounding poverty and inequality.

    Prerequisite: ( PUBP 001  and PUBP 100  and ECON 100  and PSY 105 ) or ECON 110 . Normal Letter Grade only.


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  • PUBP 120: Health Care Policy


    [4 units]

    Examines current health policy issues and policy approaches, as a way of exploring problems in the design and implementation of policy. It concentrates on issues of access to care, quality of care, health care costs, health insurance, health behavior, and the cultural and linguistic issues facing immigrants’ access to care.

    Prerequisite: (PUBP 001  and PUBP 100  and ECON 100  and PSY 105 ) or ECON 110 . Normal Letter Grade only.


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  • PUBP 130: Environmental Policy


    [4 units]

    Examines current environmental policy as a way of exploring problems in the design and implementation of policy. Provides an overview of basic concepts and methods of environmental policy analysis and implementation looking at a range of local and global environmental policy issues, such as environmental justice, air quality, and urbanization.

    Prerequisite: (PUBP 001  and PUBP 100  and ECON 100  and PSY 105 ) or ECON 110 . Normal Letter Grade only.


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  • PUBP 140: Immigration and Public Policy


    [4 units]

    Examines the origins, consequences, and characteristics of immigrants to the United States, from the nineteenth century to the present. We look at social and economic forces behind immigration; the impact of immigrants; and their process of integration. We also examine various debates on immigrant and immigration policy.

    Prerequisite: (PUBP 001  and PUBP 100  and ECON 100  and PSY 105 ) or ECON 110 . Normal Letter Grade only.


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  • PUBP 150: Race, Ethnicity and Public Policy


    [4 units]

    Examines the ways in which policies are shaped by and respond to issues of race, ethnicity and culture. Among others, we explore issues of inequality in the labor market, segregation, discrimination, environmental justice, health care access, and social and political inequality.

    Prerequisite: (PUBP 001  and PUBP 100  and ECON 100  and PSY 105 ) or ECON 110 . Normal Letter Grade only.


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  • PUBP 192: Internship in Public Policy


    [1-4 units]

    Provides oversight and structure for a student’s internship in a field of public policy in community organizations, professional research projects, etc. connected to the study of public policy. Requires students to write an original research paper or relevant product that demonstrates how the internship advanced their knowledge of public policy.

    Open only to standing(s): Junior, Senior. Permission of instructor required. Pass/Fail only. Course may be repeated 2 times for credit.


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  • PUBP 195: Upper Division Undergraduate Research


    [1-4 units]

    Supervised research.

    Permission of instructor required. Course may be repeated for credit.


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  • PUBP 198: Upper Division Directed Group Study


    [1-5 units]

    Group directed study.

    Permission of instructor required. Pass/Fail only. Course may be repeated for credit.


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  • PUBP 199: Upper Division Individual Study


    [1-4 units]

    Course involves an independent research project under the supervision of a Public Policy faculty member. To be taken in the senior year.

    Prerequisite: PUBP 100  and ECON 100  and (PSY 105  or ECON 110 ). Permission of instructor required. Course may be repeated 2 times for credit.


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Quantitative and Systems Biology

  
  • Syllabus

    QSB 200: Molecular Cell Biology


    [3 units]

    A graduate-level course focusing on molecular aspects of cellular processes, including signal transduction, cell division, differentiation, protein synthesis and degradation, and regulation of gene expression. Each topic is accompanied by critical evaluation of classic papers and recent publications.

    Prerequisite: Upper-division undergraduate courses in cell and molecular biology. Normal Letter Grade only.


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  • QSB 201: Teaching and Learning in the Sciences


    [1 unit]

    Students are introduced to ‘scientific teaching’ - an approach to teaching science that uses many of the same skills applied in research. Topics include how people learn, active learning, designing, organizing and facilitating teachable units, classroom management, diversity in the classroom and assessment design.

    Permission of instructor required. Satisfactory/Unsatisfactory only. Discussion included.


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  • QSB 202: Graduate Level Biochemistry


    [3 units]

    The overall objective of QSB 202 is to teach students fundamental principles and concepts of biochemistry as a scientific discipline at the graduate level. The emphasis will be on the relationship between macromolecular structure and function.

    Prerequisite: BIO 101  and BIO 102  or equivalent courses. Normal Letter Grade only.


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  • QSB 207: Physical Biochemistry


    [3 units]

    Physical Biochemistry is the study of properties such as macromolecular folding, multimerization, structure, and ligand binding. This course will instruct students on these, and on the experimental techniques that can quantitatively probe these properties, including hands-on work with multidimensional NMR data. Also included is in-depth discussion of recent biophysical literature.

    Normal Letter Grade only. Conjoined with BIO 107 .


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  • Syllabus

    QSB 211: Advanced Neurobiology: Development, Physiology and Behavior


    [3 units]

    Team-taught graduate level advanced neurobiology. Covers advanced concepts in electrophysiology, neuronal signal transduction, brain development, synaptic plasticity, learning and memory, genes and environmental effect on behavior. In addition to lectures, students will be required to read, discuss and critique current research papers relevant to the field.

    Permission of instructor required. Normal Letter Grade only. Course may be repeated 1 time for credit.


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  • QSB 212: Advanced Signal Transduction and Growth Control


    [4 units]

    Signal transduction in mammalian cells with emphasis on molecular and genetic regulation of these processes and their role in cell function. Graduate requirement includes an advanced discussion section involving research methodology and data interpretation led by the instructor.

    Prerequisite: Any undergraduate biochemistry course.


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  • QSB 214: Tissue Engineering Design


    [3 units]

    Fundamental topics include: issues related to the cell source (including stem cells, plasticity, transdifferentiation, therapeutic cloning vs. reproductive cloning, bone marrow transplants, and cell differentiation and purification), cell culture and tissue organization, gene therapy delivery methods, cell adhesion and migration, issues in construct design, tissue preservation, and immunoisolation and/or modulation. Current case studies and issues for FDA approval of tissue engineered products are also covered.

    Prerequisite: MATH 021 , PHYS 008  and BIO 002  or equivalent. Cross-Listed with BEST 214 . Conjoined with BIOE 114 .


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  • QSB 215: Principles of Biological Technologies


    [3 units]

    The principles underlying commonly used and cutting-edge technical procedures in biological research. Lectures and primary literature critiques on biochemical, molecular, cellular, bioengineering and computational techniques.

    Prerequisite: QSB 290 . Discussion included.


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  • QSB 217: Lab on a Chip: Developing 3rd World Diagnostics for Global Health


    [3 units]

    This is the first-ever four campus course between UC San Francisco, UC Berkeley, UC Santa Cruz, and UC Merced which aims to 1) raise awareness and knowledge about global health issues 2) teach students critical engineering skills such as nano/micro-fabrication 3) enable students to design, build, and test their own diagnostics and 4) develop entrepreneurial skills. Students learn about tuberculosis from leading experts at UCSF and then address the dearth of sensitive diagnostics by designing and testing their own nano/micro-systems. Taught at UC Merced with tele-conferencing to the other campuses and two field trips. Funded in part by QB3.

    Normal Letter Grade only. Laboratory included. Cross-Listed with BEST 217 .


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  • QSB 218: Global Change Biology


    [3 units]

    Addresses different global change processes (climate change, habitat fragmentation, ozone pollution etc.); their impacts on organisms; and interactions and feedbacks between various global change factors and biological processes. Readings are taken from the recent scientific literature. Students will write a review article on a topic of their choice.

    Normal Letter Grade only. Cross-Listed with ES 218 .


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  • QSB 220: Cellular Microbiology


    [3 units]

    Emphasizes the molecular basis of interaction between microbial pathogens (bacteria, viruses and protozoan parasites) and host cells. We also include discussion of the immune response to infection. Student-led presentations and discussion of reading assignments from the current scientific literature.

    Normal Letter Grade only. Discussion included.


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  • QSB 223: Human Parasitology


    [4 units]

    Covers the biology, parasitism and pathogenesis of parasites that cause significant human disease—the parasitic helminthes and the protozoan parasites. How each parasite establishes infection in their hosts, how it spreads between hosts, and the pathogenesis of disease. Current approaches to control parasitic disease will be addressed. Cutting edge science with a focus on new molecular concepts will be addressed during an additional one hour lecture/discussion session specifically for graduate students.

    Open only to major(s): Quantitative and Systems Biology. Normal Letter Grade only. Discussion included. Conjoined with BIO 123 .


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  • QSB 227: Virology


    [3 units]

    Overview of viruses, focusing on structure, infecting cycle, interactions with host, transmission and methods of detection and control.

    Prerequisite: QSB 290 . Normal Letter Grade only. Discussion included. Conjoined with BIO 127 .


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  • QSB 241: Advanced Genomic Biology


    [4 units]

    Comprehensive introduction to the language of genes and genomes, including genotype to phenotype relationships, gene regulation of development and disease, sources of phenotypic variation, and organization of genomes across the domains of life. Graduate requirements include advanced discussion section led by instructor and genome informatics project.


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  • QSB 242: Genome Biology


    [5 units]

    Introduction to the concepts behind genome biology and a detailed overview of the many tools used in comparative genomics. Specific topics include genome assembly, gene modeling and comparative genomics, transcriptomics, and proteomics of prokaryotic and eukaryotic organisms. Students carry out real scientific projects in collaboration with course faculty and produce new genomic data of publishable quality.

    Prerequisite: BIO 141 . Normal Letter Grade only. Discussion, Laboratory included.


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  • QSB 244: Phylogenetics: Speciation and Macroevolution


    [4 units]

    Provides the theory behind reconstruction of evolutionary relationships and introduces the comparative methods and tools of phylogenetics. Topics include use of morphological, molecular, and fossil data in distance, parsimony, likelihood, and Bayesian frameworks for investigating geographic patterns and rates of speciation, phenotypic evolution, diversification, extinction, and biogeography.

    Normal Letter Grade only. Discussion included. Cross-Listed with ES 244 .


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  • QSB 244L: Phylogenetics Laboratory: Speciation and Macroevolution


    [1 unit]

    Practice in reconstruction of evolutionary relationships and introduces the comparative methods and tools of phylogenetics. Topics include morphological, molecular, and fossil data in distance, parsimony, likelihood, and Bayesian frameworks for investigating geographic patterns and rates of speciation, phenotypic evolution, diversification, extinction, and biogeography.

    Corequisite: QSB 244 . Normal Letter Grade only. Laboratory included.


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  • QSB 245: Biogeography


    [3 units]

    Explores a diversity of current topics in Biogeography, providing an overview of the field’s history, development, and a prospectus for its near future. We will consider relevant methods, advances in related fields, and application of biogeographic information in a changing world.

    Normal Letter Grade only. Course may be repeated 3 times for credit. Cross-Listed with ES 245 .


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  • Syllabus

    QSB 246: Community Ecology


    [3 units]

    Major themes and current topics in community ecology, including patterns in the diversity, abundance, and composition of species in communities and the processes underlying these patterns such as environmental filtering, species interactions, evolutionary history, and neutral processes.

    Prerequisite: BIO 148  recommended. Cross-Listed with ES 246 .


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  • QSB 248: Advanced Topics in Ecology


    [3 units]

    Utilizes directed readings and discussion of classical and current literature in ecology, including physiological, population, community, ecosystem, landscape, and global ecology studies.

    Normal Letter Grade only. Discussion included. Cross-Listed with ES 248 .


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  • QSB 249: Topics in the History, Philosophy, and Practice of Science


    [3 units]

    Explores special topics in the history, philosophy, and practice of science, such as the nature of interdisciplinary interactions, the concept of “paradigm shift”, relationships between politics and science, and the influence of new technologies. Does not fulfill the “third course requirement” of QSB degrees except by petition to QSB EPC.

    Normal Letter Grade only. Course may be repeated 3 times for credit. Cross-Listed with ES 249 .


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  • QSB 250: Embryos, Genes and Development


    [3 units]

    Principles of developmental biology as revealed through analysis of invertebrate and vertebrate system. Animal models are used to examine the molecular and cellular mechanisms that influence cell fate. Cell signaling is studied in the context of embryonic pattern formation and the development of body plans and organ systems. Read, discuss and critique current research papers relevant for the field.

    Prerequisite: QSB 290  and (BIO 110  or equivalent course). Normal Letter Grade only. Discussion included. Conjoined with BIO 150 .


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  • QSB 251: Advanced Molecular Immunology


    [3 units]

    A comprehensive introduction to advanced principles of immunology. Topics include innate immune defense, immunoglobulin gene rearrangements, antigen presentation, lymphocyte trafficking, regulation of lymphocyte development, lymphocyte activation and effector functions, dendritic cell biology, immune response to infection and diseases of the immune system. Sessions will consist of lectures, student presentations and discussion of seminal and current research articles.


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  • QSB 252: Cancer Genetics and Tumor Biology


    [3 units]

    Topics include viral and hormonal carcinogenesis, molecular aberrations in cancer, tumor development, epigenetic and cancer, tumor immunology, oncogenes.

    Open only to major(s): Quantitative and Systems Biology. Normal Letter Grade only.


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  • QSB 253: Evolution and Development


    [3 units]

    Compare and contrast the developmental cues of a variety of animals and emphasizes how conserved developmental pathways have been manipulated through evolutionary processes to produce different physical features. The effects of regulatory region mutations, gene duplication, and genetic co-opting will be investigated.

    Permission of instructor required. Normal Letter Grade only. Discussion included. Conjoined with BIO 153 .


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  • QSB 256: Ecological Dynamics


    [4 units]

    Survey of theoretical ecology, involving a tour through population dynamics, stochastic processes, and ecological networks. Both analytical and numerical (computational) approaches will be used to build and examine dynamic models, as well as to assess the role of theoretical vs. empirical approaches to understand the ecological processes.

    Discussion included. Cross-Listed with ES 256 .


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  • QSB 261: Human Physiology


    [3 units]

    Understanding the mechanisms underlying function of major human organs. Emphasis includes neural transmission and action potential, cardiovascular, renal and gastrointestinal physiology, metabolism, and endocrinology. Laboratory experiments demonstrating and reinforcing topics covered in lecture with an emphasis on scientific method. Discussion section critically reads and evaluates papers in physiology and provide an opportunity for the students to practice presenting scientific data to an audience.

    Permission of instructor required. Normal Letter Grade only. Discussion, Laboratory included. Conjoined with BIO 161 .


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  • QSB 270: Academic Writing in Graduate Studies


    [3 units]

    Designed to increase the writing proficiency of graduate students, with a focus on strategies for reading critically, organizing and developing thoughts, choosing appropriate vocabulary, and generating and revising writing in a given scientific field. Topics address scientific disciplines. Projects may include writing abstracts, research reports, literature reviews, posters, and grant proposals.

    Open only to major(s): Quantitative and Systems Biology, Chemistry and Chemical Biology, Physics, Applied Mathematics. Cross-Listed with CHEM 270 , MATH 270 , PHYS 270 .


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  • QSB 271: Advanced Neurobiology: Brain Dysfunction and Neurodegenerative Diseases


    [3 units]

    In-depth cellular, molecular and genetic based mechanisms of brain dysfunctions by drug abuse, altered neuronal activities, and neurodegenerative diseases. Fundamental neurobiology of the central nervous system, pharmacology/toxicology, biochemistry, anatomy and genetics of the brain will be covered.


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  • QSB 280: Advanced Mathematical Biology


    [3 units]

    Graduate level mathematical modeling and data analysis skills for life science researchers taught through hands-on computational laboratories. Topics include population models, predator-prey and competition systems, epidemic models with applications to sexually transmitted diseases, dynamic diseases, enzyme kinetics, biological oscillators, and switches.

    Normal Letter Grade only. Discussion included. Conjoined with BIO 180 .


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  • QSB 281: Molecular Dynamics and Biomolecular Simulation


    [4 units]

    Uses lectures and laboratory exercises to teach the practice of biomolecular modeling. Topics include classical molecular dynamics, molecular mechanics and visualization. The laboratories involve simulations of systems including water, DNA and proteins. The course includes two projects for the students to apply molecular simulation to their graduate research.

    Normal Letter Grade only. Discussion, Laboratory included. Cross-Listed with CHEM 281 . Conjoined with BIO 181 , CHEM 181 .


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  • QSB 282: Bioinformatics


    [5 units]

    Graduate level introduction to tools, algorithms, statistics, and databases used in bioinformatics, emphasizing an open-source, command-line toolbox approach. Topics covered as in BIO 182 , plus critical assessment of bioinformatics literature, introduction to Perl, and an independent research project. Mandatory computer laboratory, for which prior programming experience is helpful but not assumed.

    Discussion, Laboratory included.


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  • QSB 283: Population Genetics


    [3 units]

    The various factors that affect gene flow and frequency within a population. Theories of selection, neutrality, drift, hitchhiking, recombination, mutation, isolation, in-breeding, and selfish genetic elements are taught along with statistical tests and experimental methods for detecting these forces.

    Normal Letter Grade only. Discussion included. Conjoined with BIO 183 .


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  • QSB 285: Biostatistics


    [4 units]

    For graduate students in QSB desiring to learn more about statistical inference and methods for the analyses of biological datasets. Covers probability, linear and logistic regression, multivariate models, parametric and non-parametric models, bootstrap, hypothesis testing and causal inference. Students will also read papers and reproduce some of the main statistical analyses for homework. For the final project students will choose a dataset of their choice to analyze. Otherwise the instructor will pick one for them. Students will write reports and give a final presentation of their data analysis

    Prerequisite: Prior knowledge of calculus, linear algebra, and programming strongly recommended. Open only to major(s): Quantitative and Systems Biology. Normal Letter Grade only. Discussion included.


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  • QSB 289: Research Forums in Quantitative and Systems Biology


    [3 units]

    Research forums involve cooperative discussions about literature and research led by at least two faculty preferably from different disciplines, giving graduate students practice in engaging in scientific communication, scholarship, interdisciplinary research exchange and identification of open research problems. In a typical week, about one half of contact hours would consist of faculty presentation of key literature around a certain scientific concept or technique, and one half of student presentations of additional literature applying that concept or technique, coverage and integration of diverse scientific literature, and group discussion.

    Course may be repeated for credit. Discussion included.


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  • QSB 290: Current Topics in Quantitative and Systems Biology


    [3 units]

    Principles and applications of systems and synthetic biology to the investigation and engineering of biological systems of all kinds, from macromolecules to ecosystems. Integrated coverage of core concepts and techniques with current literature and connections to current research in QSB at UC Merced. Group and individual assessments include oral presentation and discussion of literature, interdisciplinary synthesis through written reviews and a final white paper research proposal applying systems and synthetic biology to individual research interests.

    Normal Letter Grade only. Course may be repeated 1 time for credit. Discussion included.


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  • Syllabus

    QSB 291: Research Forums in Quantitative and Systems Biology


    [1 unit]

    Seminar series covering current topics in quantitative and system biology presented by visiting speakers chosen by QSB faculty and students with occasional presentations by UC Merced faculty and student members of QSB.

    Satisfactory/Unsatisfactory only. Course may be repeated for credit.


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  • Syllabus

    QSB 292: Quantitative and Systems Biology Group Meeting


    [1 unit]

    Meetings to describe current progress and research plans lead by individual QSBGG faculty.

    Normal Letter Grade only. Course may be repeated for credit. Cross-Listed with BEST 292 .


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  • QSB 293: Quantitative and Systems Biology Journal Club


    [1 unit]

    Student-led presentation, analysis, and discussion of reading assignments from the scientific literature.

    Normal Letter Grade only. Course may be repeated for credit. Discussion included. Cross-Listed with BEST 293 .


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  • Syllabus

    QSB 294: Responsible Conduct of Research


    [1 unit]

    Seminar covering responsibilities and expectations for researchers as well as advice for success in graduate school and science careers, required for NIH-funded graduate students.

    Satisfactory/Unsatisfactory only. Cross-Listed with BEST 294 .


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  • Syllabus

    QSB 296: Professional Skills Development


    [3 units]

    To introduce incoming and continuing graduate students to the art of grantsmanship and effective scientific communication. Will also emphasize manuscript preparation and critique, and oral presentation skill development.

    Enrollment priority given to first year School of Natural Sciences QSB graduate group. Enrollment by students in other SNS graduate groups will be considered. Normal Letter Grade only. Discussion included.


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  • QSB 297: Systems Biology: From Molecules to Metabolic Networks


    [3 units]

    A rigorous introduction to the theories, tools, and applications of systems biology. The course is organized around the biological flow of information known as the central dogma of biology. In essence we translate DNA into RNA and extend this information into metabolic and cellular networks. The course introduces experimental and high throughput approaches for generating large datasets, theory, algorithms, and computational approaches for their analysis. Data for analysis will come from ongoing systems biology projects taking place in the Instructor’s lab (genomics, transcriptomics, proteomics, metabolomics, fluxomics) as well as those of collaborators at UC Merced and other nearby institutions (metagenomics, phosphoproteomics, chenomics). The course may take advantage of presentations by guest lecturers with expertise in one of the many aspects of systems biology, or one of the sciences upon which it crucially depends.

    Normal Letter Grade only.


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  • QSB 298: Directed Group Study


    [1-12 units]

    Group project under faculty supervision.

    Permission of instructor required. Course may be repeated for credit. Laboratory included.


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  • QSB 299: Directed Independent Study


    [1-12 units]

    Independent project under faculty supervision.

    Permission of instructor required. Grading option is instructor preference. Course may be repeated for credit.


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  • QSB 399: University Teaching


    [1 unit]

    Centered on a student’s classroom experiences as a Teaching Assistant in an undergraduate Biological Sciences course. Provides a faculty-directed opportunity to implement teaching practices presented in the course Teaching and Learning in the Sciences. Involves video-taping of teaching, peer review, and weekly meetings with faculty.

    Corequisite: QSB 201  or MATH 201 . Permission of instructor required. Must hold at least a 25%-time appointment as a Teaching Assistant for an undergraduate course in BIO. Satisfactory/Unsatisfactory only. Course may be repeated 1 time for credit. Discussion, Laboratory included.


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Social Sciences

  
  • SCS 090X: Freshman Seminar


    [1 unit]

    Examination of a topic in the social, behavioral and cognitive sciences.

    Course may be repeated 1 time for credit.


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  • SCS 095: Lower Division Undergraduate Research


    [1-5 units]

    Supervised research.

    Permission of instructor required. Course may be repeated for credit.


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  • SCS 098: Lower Division Directed Group Study


    [1-5 units]

    Instructor directed study for groups of lower division status.

    Permission of instructor required. Pass/Fail only. Course may be repeated for credit.


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  • SCS 099: Lower Division Individual Study


    [1-5 units]

    Instructor directed study for groups of lower division status.

    Permission of instructor required. Pass/Fail only. Course may be repeated for credit.


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  • SCS 140: Psychology and Economics


    [4 units]

    A review of psychological and economic research on departures from perfect rationality, self-interest, and other classical assumptions of economics. The implications of these new findings for classical economics are explored.

    Prerequisite: (PSY 001  or equivalent exam) and (ECON 001  or equivalent exam). Discussion included.


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  • SCS 145: Second Language Learning and Bilingualism


    [4 units]

    Issues in second language acquisition, including processing of linguistic information by bilinguals (perception, recall, translation), structure of bilingual discourse, child bilingualism, language maintenance or shift, with particular focus on the North American Context.

    Prerequisite: PSY 001  or equivalent exam. Discussion included.


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  • SCS 192: Integrative Topics


    [4 units]

    Special topics that integrate theory or research from more than one discipline in the social and behavioral sciences.

    Prerequisite: PSY 001  or ECON 001  or SOC 001  or POLI 001  or equivalent exam. Course may be repeated 1 time for credit. Discussion included.


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  • SCS 195: Upper Division Undergraduate Research


    [1-5 units]

    Supervised research.

    Permission of instructor required. Course may be repeated for credit.


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  • SCS 198: Upper Division Directed Group Study


    [1-5 units]

    Group study for upper division students.

    Open only to standing(s): Junior, Senior. Permission of instructor required. Pass/Fail only. Course may be repeated for credit.


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  • SCS 199: Upper Division Individual Study


    [1-5 units]

    Individual directed study for upper division students.

    Open only to standing(s): Junior, Senior. Permission of instructor required. Pass/Fail only. Course may be repeated for credit.


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  • SCS 210: Philosophy of Cognitive Science


    [4 units]

    Consideration of philosophical and foundational issues in cognitive science, such as: behaviorism, functionalism, the Turing Test, the Chinese Room argument, the nature of cognitive architecture, animal cognition, connectionism vs. symbolic artificial intelligence, consciousness, the self, free will, embodiment, and ethics.

    Open only to major(s): Social Sciences, Sociology, Social and Cognitive Sci. Normal Letter Grade only. Discussion included.


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  • SCS 295: Graduate Research


    [1-12 units]

    Supervised research.

    Permission of instructor required. Course may be repeated for credit. Laboratory included.


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  • SCS 298: Directed Group Study


    [1-12 units]

    Group project under faculty supervision.

    Permission of instructor required. Satisfactory/Unsatisfactory only. Course may be repeated for credit. Laboratory included.


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  • SCS 299: Directed Independent Study


    [1-12 units]

    Independent project under faculty supervision.

    Permission of instructor required. Satisfactory/Unsatisfactory only. Course may be repeated for credit.


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Sociology

  
  • SOC 001: Introduction to Sociology


    [4 units]

    The study of groups, culture, collective behavior, classes and caste, community and ecology, role, status, and personality.

    Discussion included.


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  • SOC 009: Community Mobilization and Politics


    [4 units]

    Examination of political and social mobilization at the local level, including strategies for organization and advocacy.

    Discussion included. Cross-Listed with POLI 009 .


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  • SOC 010: Statistics for Sociology


    [4 units]

    An introduction to the logic and use of statistical techniques in sociological research. By the end of the course, students will have the tools to appreciate and evaluate social research, and a foundation for conducting statistical social research themselves.

    Prerequisite: MATH 005  or MATH 011  or MATH 021  or equivalent exam. Normal Letter Grade only. Laboratory included.


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  • SOC 015: Sociological Research Methods


    [4 units]

    Provides students with a basic understanding of how to conduct social science research. Topics will include the logic of research design, issues of conceptualization and measurement, the range of data collection methods available to social scientists, and what social scientists do with data once they have collected it.

    Open only to standing(s): Sophomore, Junior, Senior. Normal Letter Grade only. Discussion included.


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  • SOC 020: Social Problems


    [4 units]

    Examines the perceptions, theories, arguments, and proposed solutions to the most vexing social issues. Explanations of these problems can be grouped into micro, meso, and macro levels of analysis. In addition, for the last 100 years researchers have examined the overlap between different social problems.

    Discussion included.


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